Originally posted on The Australian Cell Cycle Community:
The 15th Australian Cell Cycle Meeting will be held from Monday the 30th of March to Wednesday the 1st of April, 2015 at the Powerhouse Museum, in Sydney Australia.
We are also very excited and pleased to also announce that Plenary Lectures will be given by two world class experts Prof. Andrea Musacchio and Prof. Jan Karlseder.
Registration and further information will be announced soon.
Looking forward to seeing you all in Sydney Australia for #ACCM2015.
Prof. Andrea Musacchio
Director, Department of Mechanistic Cell Biology
Max-Planck Institute of Molecular Physiology
Great news, Cell Division Lab and Dr Andrew Burgess will be presenting a Poster of some of our latest research at the 29th International Association for Breast Cancer Research Conference (#IABCR14). The conference will be held from the 14 – 17 September 2014 at The Novotel Sydney Manly, New South Wales, and has an amazing line up of world class speakers, is is sure to be an excellent conference.
Are you interested in Cancer Research and want to do a PhD at the Garvan?
Then come along to the open day and where you can meet with all the supervisors, discover some amazing projects, and get all the information you need to start your career in Cancer Research.
- Date: Wednesday 10th of September 2014
- Time: 1.45-5pm
- Venue: The Kinghorn Cancer Centre, Garvan Institute of Medical Research, 370 Victoria St, Darlinghurst
Registration is free but limited to the first 25 registrants, and closes at 4.00 pm on Tuesday, 09th Sep 2014.
UPDATE: ImpactStory is not free, as I first thought, they currently have a 30 day free trail, then the cost is $45/year.
Its clear that judging a researchers output purely on the impact/quality of the journal they do/don’t publish is not always the best way to accurately judge individual achievement and output. To that end, article level metrics have recently emerged as a potential way to generate a more accurate picture of a individual researchers output.
I hadn’t really taken much notice of article metrics, however a friend at work recently told me about Impactstory, a new website that is….
an open-source, web-based tool that helps researchers explore and share the diverse impacts of all their research products—from traditional ones like journal articles, to emerging products like blog posts, datasets, and software
Its very quick and easy to signup and quickly get a snapshot of your article specific metrics. You can see my results here [link].
Interestingly, my PlosOne paper is ranked 3rd, above the 4th placed EMBO publication, which according to the traditional Impact Factor measurement would be viewed as a much, much, much better publication.
Another player in this space is ResearchGate, which has been around for much longer. It gives you a RG score, which “takes all your research and turns it into a source of reputation”.
How does the RG Score work?
Your RG Score is calculated based on how other researchers interact with your content, how often, and who they are. The higher their score, the more yours will increase.
Here is an example of what a profile looks like:
Its going to be very interesting to see how these new metrics impact on the judging of individual scientists output, and if, when and which metric grant funding bodies will prefer.
Great list of all the latest impact factors for the top cell biology journals
Originally posted on Science Tech Blog:
Here are the latest (2013) impact factors for the top journals in the field of biology, and cancer research. Its not a complete list but its a good start and a great way to find that perfect journal to publish your latest and greatest research in.
|Journal||2013||5 year 2013|
|Nat Cell Biol||20.058||21.241|
|Sci Transl Med||14.414||12.701|
|J Cell Biol||9.688||10.398|
|Nuc Acid Res||8.808||8.378|
|J Mol Cell Biol||8.432||8.953|
|Cell Death Differ||8.385||8.345|
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Great news, there is a new Electronic Lab Notebook (ELN) out on the market, and is originates in part from the makers of the excellent Papers App.
Its still very much beta software, but the roadmap looks promising. Based on my limited testing so far the program seems very easy to use, an not as overly complicated as some of the other ELN out there, which I have often found overkill for my personal needs, and consequently too expensive. The bit I like the most is that the software does not depend on a server, and thus if the developers go bust, you still have the software, and your ELN. Perhaps the best bit so far is the price which is only $29 AUD, very reasonable, and thankfully no ongoing yearly subscription fees.
Looking forward to trying this out more over the next 6 months.
There has been a bit of press lately suggesting that Antioxidants might actually be bad for cancer… not good as they are commonly promoted in the media.
IFLS has put together a great article on some of the reasons why antioxidants might not be such a great thing [Link].
In addition, we recently wrote a review article about how different ‘stresses’ including oxidation can affect mitosis, and cancer. We also came to a similar conclusion in our review, that antioxidants were a complicated and not always benifical for treating cancer. One of the main reason we suggested this was due to the fact that many common antioxidants are part of the Flavonoid family. On the surface that sound great, but many Flavonoids also happen to potently inhibit cyclin dependent kinases (Cdks). Coincidentally, our other recent article in Cell Cycle, showed that partial inhibition of Cdk1 can dramatically disrupt mitosis and drive severe cytokinesis defects and polyploidy (see video below). These mitotic defects are the foundation of chromosome instability (CIN), which is a hallmark of more aggressive cancer types, that are also resistant to most chemotherapies and treatments. In simple terms, there is a possibility that in some cases, taking large quantities of dietary Flavonoids (e.g red wine, dark chocolate etc) could drive the formation of more aggressive cancers. This is definitely an area that needs a lot more research, and as always make sure that you fully discuss any dietary and supplements with your oncologist.
This is what happens when a ‘fairly normal’ cancer cell is treated with low doses of a Cdk1 inhibitor.
Here is a picture of a polyploid cancer cell, which was produced by partially inhibiting Cdk1.
Great News…. As a part of National Science Week here in Australia, Cell Division Lab will be co-representing the Garvan Institute at a very special event hosted by ScienceAlert “Space Oddity: A Special Science Week Event With Chris Hadfield“
Take your protein pills and put your helmet on and join astronaut Chris Hadfield in celebrating National Science Week. The former commander of the International Space Station became the coolest astronaut in the world when he recorded David Bowie’s “Space Oddity” in zero gravity. Since returning to Earth, the Canadian astronaut has inspired audiences across Europe and North America with live talks on space, science and achieving your dreams.
Now he’s heading to Australia for the first time, and in his only Sydney shows he’ll be appearing alongside social media celebrities Derek Muller (Veritasium), Dr Carin Bondar (Scientific American, Discovery) and Destin Sandlin (Smarter Every Day).
The live events will feature a blend of science talk, inspiring stories and performances. If you’re not already fascinated by science, you will be by the end of it.
There are still tickets available for the Adult show starting at 8pm. But you better be quick because the all ages show sold out in less than 10 hours.
You can buy your tickets here
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Great post and great blog on all things relating to fluorescent microscopy.
Originally posted on greenfluorescentblog:
In most microscopy images that are published in research papers, there appears a scale bar. The scale bar is like a ruler that allows you to compare sizes and distances in images from different sources. Although a scale bar is helpful for assessing by eye, many image processing programs allows you to measure distances in the image. The problem is that these measurements are in pixels. That is what I encountered when I wanted to measure certain objects in my images. How to convert from pixels to nanometers (or microns) requires a simple formula and some prior data as follows:
- Objective magnification
- Lens magnification (in some microscopes, it is possible to get extra mag of 1.25x, 1.6x or 2x.
- C mount (is usually 1x)
- Pixel size – is the actual pixel size of the camera that is attached to the microscope.
- Binning – i.e. combining a cluster of pixels to a…
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