Were the front cover feature image on this months issue of Cell Cycle !

Some more good news to coincide with today’s official release of our manuscript, one of our images has been chosen to be the feature image on the front cover. It’s a great honour, one that I am very proud of, and is the first time I have ever had a front cover ! You can […]

Cell Division Lab is now on Flickr !

We now have a Flickr page where we will be uploading and storing all of our images. You can find us here and feel free to share our pics!

IncuCyte Zoom Video Tutorial and User Guide

Here is a guide that was written by Rachael McCloy from our lab on how to use the IncuCyte Zoom Kinetic Imaging System. We recently published a paper using this machine in Cell Cycle Part 1- How to set up an experiment Part 2- How to analyse an experiment Incucyte ZOOM User Guide NB: Click here to […]

A brief introduction to Mitosis

Here is a slide that I made and often use at the beginning of my talks to briefly explain what mitosis is. The images are taken from a live cell that we have labelled with fluorescent probes to highlight the DNA (red) and microtubules (green). Enjoy !

Seminar: How I got a Post-Doc Job.

Here is a short seminar that I gave to the PhD students at the end of 2013. If gives a brief over-view of the do’s and don’ts on how to get a Post-Doc position. From finding a lab, to writing the intro email. Hope its helpful.

Cell Image of the Week – Mitotic Catastrophe

Here is one of the images that we took using a Leica SP8 confocal microscope this week in the lab. It is a 3D image of a HeLa cell that has completely stuffed up mitosis (undergone mitotic catastrophe). It has separated whole chromosomes randomly into 2 daughter cells instead of separating the two identical chromatids in […]

A brief Intro to Greatwall Kinase…The King of Mitosis

Our favourite protein in the lab is Greatwall kinase. It was first discovered in 2004 to be critical for cell division in fruit flies (1,2) . The trail then went cold for a few years as to its exact function, but in 2009, while I was working as a post-doc in France, I was fortunate […]

Cell Brains – Image of the Week

Here is a HeLa cell in the first stages of mitosis (prophase) just as it has begun to condensing its DNA into chromosomes. At this point it looks strikingly similar to the folds of a human brain. The image has been put through a few photoshop filters to give this stunning final image.

Stills from Live Imaging of Human Cancer Cell

Here are a few nice still images which were taken from single frames of a timelapse movie that we did recently with some human (HeLa) cancer cells that we have constructed to stable over-express fluorescently labelled LifeAct (green) and histone H2B (red).

More new Movies of Live Cancer Cells

We have been busy constructing some new cell lines that stably express multiple fluorescently tagged proteins so that we can visualise different aspects of mitosis in real-time. The results have been stunningly beautiful. You can check them out on our Vimeo Channel Enjoy