A brief Intro to Greatwall Kinase…The King of Mitosis

Our favourite protein in the lab is Greatwall kinase. It was first discovered in 2004 to be critical for cell division in fruit flies (1,2) . The trail then went cold for a few years as to its exact function, but in 2009, while I was working as a post-doc in France, I was fortunate […]

Persin Paper on reversal of Tamoxifen resistance Now Online !

Rachael’s Paper is now on-line [Link] Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells “The cytotoxic effects of persin are CASP-4 dependent and mediated by CHOP-dependent and -independent ERS signalling cascades. Increased ERS signalling contributes to persin-induced reversal […]

Paper Accepted – Congratulations Rachael !

A Big congratulations to Rachael from our lab who just got her first, 1st Author publication accepted into BJC. A lot of hard work and persistence, and very well deserved. Will post a link to the article once its available online.