New Co-author publications in Cancers and JCI

Its been a big month for publications, with 2 new co-author papers coming out. The first entitled “Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling” was published in the prestigious Journal of Clinical Investigation (JCI). [Link] Ligand-dependent activation of Hedgehog (Hh) signaling in cancer occurs without mutations in canonical pathway genes. Consequently, the genetic […]

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New Review Published “The role of MDM2 and MDM4 in breast cancer development and prevention”

Great news, we have had a co-author review published in the Journal of Molecular and Cellular Biology. You can check out the full review here. Abstract The major cause of death from breast cancer is not the primary tumour, but relapsing, drug-resistant, metastatic disease. Identifying factors that contribute to aggressive cancer offers important leads for […]

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Persin Paper on reversal of Tamoxifen resistance Now Online !

Rachael’s Paper is now on-line  [Link] Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells “The cytotoxic effects of persin are CASP-4 dependent and mediated by CHOP-dependent and -independent ERS signalling cascades. Increased ERS signalling contributes to persin-induced reversal […]

Read More Persin Paper on reversal of Tamoxifen resistance Now Online !