Great news, our latest review article “Stressing Mitosis to Death” has been accepted for publication by Frontiers in Oncology. You can access the provisional pre-press version here. The review is about how common stresses affect mitosis, and the impact these stresses can have on the blockbuster mitotic chemotherapy drug Taxol (paclitaxel) Finally here is one of […]Read More Our Latest Review Article “Stressing Mitosis to Death” is now online !
Some more good news to coincide with today’s official release of our manuscript, one of our images has been chosen to be the feature image on the front cover. It’s a great honour, one that I am very proud of, and is the first time I have ever had a front cover ! You can […]Read More Were the front cover feature image on this months issue of Cell Cycle !
You can now download the final PDF version of our latest work here: https://www.landesbioscience.com/journals/cc/article/28401/ The great news is that its also open access so anyone and everyone can view and download it. Enjoy !Read More Our Cell Cycle Paper is now Live and Open Access
Here is one of the images that we took using a Leica SP8 confocal microscope this week in the lab. It is a 3D image of a HeLa cell that has completely stuffed up mitosis (undergone mitotic catastrophe). It has separated whole chromosomes randomly into 2 daughter cells instead of separating the two identical chromatids in […]Read More Cell Image of the Week – Mitotic Catastrophe
Our favourite protein in the lab is Greatwall kinase. It was first discovered in 2004 to be critical for cell division in fruit flies (1,2) . The trail then went cold for a few years as to its exact function, but in 2009, while I was working as a post-doc in France, I was fortunate […]Read More A brief Intro to Greatwall Kinase…The King of Mitosis
I am pleased to announce that the latest publication for the lab is now available online at PLoS ONE [Link][PDF]. Below are some additional videos of the Chromotek HeLa cell line [link] undergoing cell division, with the Imaris Dot quantification overlaid, along with a instructional video on how to perform the dot quantification analysis using […]Read More New Paper Published : Quantitative Live Imaging of Endogenous DNA Replication in Mammalian Cells