New Co-author Publication: Hic1 maintains chromosomal stability independent of p53

Great news, we have a new co-author publication out in the journal Oncogene! The work was lead by Professor Neil Watkins, and is titled “The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53”. You can access the full article here [Link] ABSTRACT: Hypermethylated-in-Cancer 1 (Hic1) is a tumor suppressor gene frequently inactivated by epigenetic […]

Read More New Co-author Publication: Hic1 maintains chromosomal stability independent of p53

Switching off Cancers Diversity

A defining feature in over 2/3rds of all solid tumours is the continual loss and gain of whole are small parts of chromosomes. This instability, or CIN for short, strongly implicated in tumour initiation, progression, chemoresistance and poor prognosis. CIN is created through failures during mitosis, whereby whole or parts of a chromosome are segregated […]

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Our Latest Review Article “Stressing Mitosis to Death” is now online !

Great news, our latest review article “Stressing Mitosis to Death” has been accepted for publication by Frontiers in Oncology. You can access the provisional pre-press version here. The review is about how common stresses affect mitosis, and the impact these stresses can have on the blockbuster mitotic chemotherapy drug Taxol (paclitaxel) Finally¬†here is one of […]

Read More Our Latest Review Article “Stressing Mitosis to Death” is now online !