Great news we are currently looking for a new honours student for 2016. The title of the project is “Developing novel biosensors to monitor DNA damage in cancer cells”. Its a very exciting new project incorporating cutting edge microscopy and fluorescent biosensors. If you think you have what it takes and are interested please feel […]Read More Position available: 2016 Honours Student Project in our Lab
Great news, Cell Division Lab will be at the Sydney Light Optical Users Meeting, hosted by Dr Pamela Young at Sydney University, this Thursday (24th of July). I will be presenting a short seminar on “Imaging and Analysing Cell Division”. If you would like to attend please contact Pamela asap. Her details are below! Hope […]Read More We will be at the Sydney Light Optical Users Meeting on July 24th 2014
Some more good news to coincide with today’s official release of our manuscript, one of our images has been chosen to be the feature image on the front cover. It’s a great honour, one that I am very proud of, and is the first time I have ever had a front cover ! You can […]Read More Were the front cover feature image on this months issue of Cell Cycle !
Here is a slide that I made and often use at the beginning of my talks to briefly explain what mitosis is. The images are taken from a live cell that we have labelled with fluorescent probes to highlight the DNA (red) and microtubules (green). Enjoy !Read More A brief introduction to Mitosis
Here is one of the images that we took using a Leica SP8 confocal microscope this week in the lab. It is a 3D image of a HeLa cell that has completely stuffed up mitosis (undergone mitotic catastrophe). It has separated whole chromosomes randomly into 2 daughter cells instead of separating the two identical chromatids in […]Read More Cell Image of the Week – Mitotic Catastrophe
Our favourite protein in the lab is Greatwall kinase. It was first discovered in 2004 to be critical for cell division in fruit flies (1,2) . The trail then went cold for a few years as to its exact function, but in 2009, while I was working as a post-doc in France, I was fortunate […]Read More A brief Intro to Greatwall Kinase…The King of Mitosis
Here are a few nice still images which were taken from single frames of a timelapse movie that we did recently with some human (HeLa) cancer cells that we have constructed to stable over-express fluorescently labelled LifeAct (green) and histone H2B (red).Read More Stills from Live Imaging of Human Cancer Cell
The Garvan recently took possession of a fantastic new Leica SP8 confocal microscope, which we have been lucky enough to have play with. Here are the results from our first go with the microscope. Very impressive, and we are yet to push the system to its fully potential. The massive increase in resolution and quality […]Read More New Mitotic Movies